Pinky & Pepper Forever by Ivy Atoms. Digest size, 72 pages, full color. Published by Silver Sprocket.
This is the kind of comic a lot of people have attempted (funny animal comics with transgressive themes and wild artwork) but Atoms really makes it congeal into a real work of revolutionary comic art. You feel rules of what comics 'should be' broken down as you read this. Atoms whips you through the pages with real gusto.